inflammation

Episode 9 – the “gut-brain axis”

May 10, 2011 in Podcasts | 30 comments

In this episode we discuss the gut-brain axis: the relationship between digestive health and cognitive function, memory, depression, anxiety and other mental and behavioral health issues. We cover:the basic physiology involved how inflammation in the gut affects the brain how decreased brain activity compromises gut function how to recognize the signs and symptoms of gut-brain axis dysfunction studies demonstrating gut-brain dysfunction and its effects on health dietary and lifestyle modifications to improve gut-brain function.I think the gut-brain axis is one of ...
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9 Steps to Perfect Health – #7: Move Like Your Ancestors

March 10, 2011 in Perfect Health | 61 comments

There's no question that regular exercise is essential to health. Our paleolithic ancestors had a different word for exercise: life. For the vast majority of our evolutionary history, humans had to exert ourselves - often quite strenuously - to get food. We naturally spent a lot of time outdoors in the sun, walking, hunting, gathering, and performing various other physically-oriented tasks. We had no concept of this as “exercise” or “working out”. It ...
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How inflammation makes you fat and diabetic (and vice versa)

September 15, 2010 in Diabesity | 26 comments

In the previous article in this series, I argued that diabesity is an autoimmune, inflammatory disorder. In this article, we're going to review the evidence linking inflammation to obesity and type 2 diabetes (T2DM) and learn why inflammation may be the single-most important mechanism driving the diabesity epidemic.The inflammation-diabesity connection is a hot topic in the scientific literature. A Pubmed search for "inflammation diabetes obesity" turns up more than 1,800 articles. The association between ...
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The autoimmune-inflammatory model of diabesity

September 9, 2010 in Diabesity | 22 comments

In this article, I'd like to present a unified model of diabesity. I think it's helpful to have a "birds-eye view" of how diabesity begins and progresses. It gives us a context for the articles that will follow, each of which will examine specific elements of the model in much more detail.Two caveats before we dive in. First, remember that all models are imperfect. They're useful tools, but as the saying ...
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