insulin

Reframing the obesity debate: cause/effect, genetics & robot clones

September 5, 2011 in Diabesity | 108 comments

The more damaged you are, the more carbohydrate restriction is likely to benefit you long term. - Peter @Hyperlipid I don't think there are too many people out there familiar with the mechanisms of diabetes and insulin resistance that would disagree with that statement. But just because a low-carb diet causes fat loss in this population, that doesn't mean that carbs caused the fat gain or damaged metabolism in the first place. I wrote ...
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Why hemoglobin A1c is not a reliable marker

March 1, 2011 in Lab testing | 23 comments

Over the last few years doctors are increasingly relying on a test called hemoglobin A1c to screen for insulin resistance and diabetes. It's more practical (and significantly cheaper) than post-meal glucose testing, and it's less likely to be skewed by day-to-day changes than fasting blood glucose. What is hemoglobin A1c? Sugar has a tendency to stick to stuff. Anyone that has cooked with sugar can tell you that. In our bodies, sugar also sticks - ...
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Think skinny people don’t get type 2 diabetes? Think again.

September 19, 2010 in Diabesity | 35 comments

In the last article we discussed the complex relationship between body weight and type 2 diabetes (T2DM). We learned that although obesity is strongly associated with T2DM, a subset of "metabolically healthy obese" (MHO) people have normal blood sugar and insulin sensitivity and don't ever develop diabetes. In this article we're going to talk about the mirror reflection of the MHO: the "metabolically unhealthy nonobese" (MUN). These are lean people with either full-fledged type 2 ...
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Diabesity: the #1 cause of death and disease?

September 6, 2010 in Diabesity | 52 comments

Obesity, insulin resistance, metabolic syndrome and type 2 diabetes have reached epidemic proportions. There's not a person reading this article who isn't affected by these conditions, either directly or indirectly. Yet as common as these conditions are, few people understand how closely they're related to one another. It is now clear that not only do these conditions share the same underlying causes - and thus require the same treatment - they are 100% preventable and, ...
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