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	<title>Chris Kresser &#187; soy</title>
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	<itunes:summary>Medicine for the 21st century</itunes:summary>
	<itunes:author>Chris Kresser</itunes:author>
	<itunes:explicit>clean</itunes:explicit>
	<itunes:image href="http://chriskresser.chriskresserlac.netdna-cdn.com/images/rhrlogo.jpg" />
	<itunes:owner>
		<itunes:name>Chris Kresser</itunes:name>
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	<managingEditor>chris@chriskresser.com (Chris Kresser)</managingEditor>
	<copyright>Chris Kresser 2011</copyright>
	<itunes:subtitle>Medicine for the 21st century</itunes:subtitle>
	<itunes:keywords>health,medicine,alternative,nutrition,paleo,</itunes:keywords>
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		<item>
		<title>9 Steps To Perfect Health &#8211; #1: Don&#8217;t Eat Toxins</title>
		<link>http://chriskresser.com/9-steps-to-perfect-health-1-dont-eat-toxins</link>
		<comments>http://chriskresser.com/9-steps-to-perfect-health-1-dont-eat-toxins#comments</comments>
		<pubDate>Fri, 28 Jan 2011 15:19:53 +0000</pubDate>
		<dc:creator>Chris Kresser</dc:creator>
				<category><![CDATA[Food & Nutrition]]></category>
		<category><![CDATA[Perfect Health]]></category>
		<category><![CDATA[9]]></category>
		<category><![CDATA[food]]></category>
		<category><![CDATA[gluten]]></category>
		<category><![CDATA[gluteomorphins]]></category>
		<category><![CDATA[industrial]]></category>
		<category><![CDATA[oil]]></category>
		<category><![CDATA[seed]]></category>
		<category><![CDATA[soy]]></category>
		<category><![CDATA[steps]]></category>
		<category><![CDATA[sugar]]></category>
		<category><![CDATA[Toxins]]></category>
		<category><![CDATA[wheat]]></category>

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		<description><![CDATA[Four common food toxins - wheat, sugar, industrial seed oils and soy - are largely responsible for the epidemic of modern diseases destroying our health.]]></description>
			<content:encoded><![CDATA[<p></p><p><img class="imageright" src="http://chriskresser.chriskresserlac.netdna-cdn.com/images/doughnut.jpg" alt="doughnut" />Imagine a world where:</p>
<ul>
<li>diabetes, heart diseases, autoimmunity and other modern diseases are rare or don&#8217;t exist at all</li>
<li>we are naturally lean and fit</li>
<li>we are fertile throughout our childbearing years</li>
<li>we sleep peacefully and deeply</li>
<li>we age gracefully without degenerative diseases like Alzheimer&#8217;s and osteoporosis</li>
</ul>
<p>While this might sound like pure fantasy today, anthropological evidence suggests that this is exactly how human beings lived for the vast majority of our evolutionary history.</p>
<p>Today, most people accept diseases like obesity, diabetes, infertility and Alzheimer&#8217;s as &#8220;normal&#8221;.  But while these diseases may now be <em>common</em>, they&#8217;re <em>anything but normal</em>.  Humans evolved roughly 2.5 million years ago, and for roughly 84,000 generations we were naturally free of the modern diseases which kill millions of people each year and make countless others miserable.  In fact, the world I asked you to imagine above &#8211; which may seem preposterous and unattainable today &#8211; was the natural human state for our entire history on this planet up until a couple hundred years ago.</p>
<p>What was responsible for the change?  What transformed us from naturally healthy and vital people free of degenerative disease into a world of sick, fat, infertile and unhappy people?</p>
<p>In a word?  <strong>The modern lifestyle</strong>.  And though there are several aspects of our current lifestyle that contribute to disease, the widespread consumption of <strong>food toxins</strong> is by far the greatest offender.  Specifically, the following four dietary toxins are to blame:</p>
<ul>
<li>Cereal grains (especially refined flour)</li>
<li>Omega-6 industrial seed oils (corn, cottonseed, safflower, soybean, etc.)</li>
<li>Sugar (especially high-fructose corn syrup)</li>
<li>Processed soy (soy milk, soy protein, soy flour, etc.)</li>
</ul>
<h3>What is a toxin?</h3>
<p>At the simplest level, a toxin is something capable of causing disease or damaging tissue when it enters the body. When most people hear the word “toxin”, they think of chemicals like pesticides, heavy metals or other industrial pollutants. But even beneficial nutrients like water, which are necessary to sustain life, are toxic at high doses.</p>
<p>In their book <a href="http://www.amazon.com/Perfect-Health-Diet-Youthful-Vitality/dp/0982720904/ref=sr_1_1?ie=UTF8&#038;qid=1296139769&#038;sr=8-1" target="_blank">The Perfect Health Diet</a>, Paul &#038; Shou-Ching Jaminet apply the economic principle of declining marginal benefits to toxins:</p>
<blockquote><p>It implies that the first bit eaten of any toxin has low toxicity. Each additional bit is slightly more toxic than the bit before. At higher doses, the toxicity of each bit continues to increase, so that the toxin is increasingly poisonous.</p></blockquote>
<p>This is important to understand as we discuss the role of dietary toxins in contributing to modern disease. Most of us won’t get sick from eating a small amount of sugar, cereal grain, soy and industrial seed oil.  But if we eat those nutrients (or rather anti-nutrients) in excessive quantities, our risk of developing modern diseases rises significantly.  </p>
<p>That&#8217;s exactly what&#8217;s happening today.  These four food toxins &#8211; refined cereal grains, industrial seed oils, sugar and processed soy &#8211; comprise the bulk of the modern diet.  Bread, pastries, muffins, crackers, cookies, soda, fruit juice, fast food and other convenience foods are all loaded with these toxins.  And when the majority of what most people eat on a daily basis is toxic, it&#8217;s not hard to understand why our health is failing. </p>
<p>Let&#8217;s look at each of these food toxins in more detail.</p>
<h3>Cereal grains: the unhealthiest &#8220;health food&#8221; on the planet?</h3>
<p>The major cereal grains &#8211; wheat, corn, rice, barley, sorghum, oats, rye and millet &#8211; have become the staple crops of the modern human diet.  They&#8217;ve also become the &#8220;poster children&#8221; of the low-fat, high-carbohydrate diet promoted by organizations like the American Heart Association (AHA) and American Diabetes Association (ADA).  If you say the phrase &#8220;whole grains&#8221; to most people, the first word that probably comes to their mind is &#8220;healthy&#8221;.</p>
<p>But the fact is that most animals, including our closest relative (the chimpanzee) aren&#8217;t adapted to eating cereal grains and don&#8217;t eat them in large quantities.  And humans have only been eating them for the past 10,000 years (a tiny blip of time on the scale of evolution).  Why?</p>
<p>Because plants like cereal grains are always competing against predators (like us) for survival.  Unlike animals, plants can&#8217;t run away from us when we decide to eat them.  They had to evolve other mechanisms for protecting themselves.  These include:</p>
<ul>
<li>producing toxins that damage the lining of the gut;</li>
<li>producing toxins that bind essential minerals, making them unavailable to the body; and,</li>
<li>producing toxins that inhibit digestion and absorption of other essential nutrients, including protein.</li>
</ul>
<p>One of these toxic compounds is the protein gluten, which is present in wheat and many of the other most commonly eaten cereal grains.  In short, gluten damages the intestine and makes it leaky.  And researchers now believe that a leaky gut is one of the major predisposing factors for conditions like obesity, diabetes and autoimmune disease.  </p>
<p>Celiac disease (CD) &#8211; a condition of severe gluten intolerance &#8211; has been well known for decades.  Celiacs have a dramatic and, in some cases, potentially fatal immune response to even the smallest amounts of gluten.  </p>
<p>But celiac disease is just the tip of the iceberg when it comes to intolerance to wheat and other gluten containing grains.  Celiac disease is characterized by antibodies to two components of the gluten compound: alpha-gliadin, and transglutaminase.  But we now know that people can and do react to several other components of wheat and gluten.  The diagram below shows how wheat and gluten are broken down in the body:</p>
<p><a href="http://chriskresser.chriskresserlac.netdna-cdn.com/wp-content/uploads/wheatdiagram.png"><img src="http://chriskresser.chriskresserlac.netdna-cdn.com/wp-content/uploads/wheatdiagram.png" alt="diagram of components of wheat" title="wheatdiagram" width="461" height="589" class="alignleft size-full wp-image-1233" /></a></p>
<p>Current laboratory testing for gluten intolerance only tests for alpha-gliadin and transglutaminase, the two components of gluten implicated in celiac disease (highlighted in red in the diagram).  But as you can see, wheat contains several other components including lectins like wheat germ agglutinin (WGA), other epitopes of the gliadin protein like beta-gliadin, gamma-gliadin and omega-gliadin, another protein called glutenin, an opioid peptide called gluteomorphin, and a compound called deamidated gliadin produced by the industrial processing or digestion of gluten.</p>
<p>So here&#8217;s the thing.  Studies now clearly show that people can react negatively to all of these components of wheat &#8211; not just the alpha-gliadin and transglutaminase that celiacs react to.  And the worst part of this is that up until about 2 weeks ago, no commercial labs were testing for sensitivity to these other subfractions of wheat.</p>
<p>This means, of course, that it&#8217;s extremely likely that far more people are intolerant to wheat and gluten than conventional wisdom would tell us.  In fact, that&#8217;s exactly what the latest research shows.  Dr. Kenneth Fine, a pioneer in gluten intolerance research, has demonstrated that <strong>1 in 3</strong> Americans are gluten intolerant, and that <strong>8 in 10</strong> have the genes that predispose them to developing gluten intolerance.</p>
<p>This is nothing short of a public health catastrophe in a nation where the #1 source of calories is refined flour. But while most are at least aware of the dangers of sugar, trans-fat and other unhealthy foods, <a href="http://www.ncbi.nlm.nih.gov/pubmed/18184122" target="_blank">fewer than 1 in 8 people</a> with celiac disease are aware of their condition.  <a href="http://www.bmj.com/content/319/7204/236.full.pdf" target="_blank">A 1999 paper</a> in the British Medical Journal illustrated this well:</p>
<p><a href="http://chriskresser.chriskresserlac.netdna-cdn.com/wp-content/uploads/celiaciceberg.jpg"><img src="http://chriskresser.chriskresserlac.netdna-cdn.com/wp-content/uploads/celiaciceberg.jpg" alt="Graphic depicting incidence of undiagnosed celiac disease" title="Celiac Iceberg" width="499" height="363" class="alignleft size-full wp-image-1237" /></a></p>
<p>Patients with clinically obvious celiac disease (observable inflammation and destruction of the gut tissue) comprise only 12.5% of the total population of people with CD.  87.5% of those with celiac have no obvious gut symptoms.  For every symptomatic patient with CD, there are 8 patients with CD and no gastrointestinal symptoms.</p>
<p>But does that mean patients with CD without gut symptoms are healthy?  Not at all.  It was long believed that the pathological manifestations of CD were limited to the gastrointestinal tract.  But research over the past few decades has revealed that gluten intolerance can affect almost every other tissue and system in the body, including:</p>
<ul>
<li>brain;</li>
<li>endocrine system;</li>
<li>stomach and liver;</li>
<li>nucleus of cells;</li>
<li>blood vessels; and,</li>
<li>smooth muscle,</li>
</ul>
<p>just to name a few!</p>
<p>This explains why CD and gluten intolerance are associated with several different diseases, including type 1 diabetes, thyroid disorders, osteoporosis, neurodegenerative conditions like Alzheimer&#8217;s, Parkinson&#8217;s and dementia, psychiatric illness, ADHD, rheumatoid arthritis, migraine, obesity and more.  The table below from the <a href="http://www.bmj.com/content/319/7204/236.full.pdf" target="_blank">same 1999 BMJ paper</a> depicts the increased incidence of other diseases in patients with CD:</p>
<p><a href="http://chriskresser.chriskresserlac.netdna-cdn.com/wp-content/uploads/celiacassociations1.jpg"><img src="http://chriskresser.chriskresserlac.netdna-cdn.com/wp-content/uploads/celiacassociations1.jpg" alt="table showing associations of other diseases with celiac disease" title="celiac disease associations" width="499" height="259" class="alignleft size-full wp-image-1235" /></a></p>
<p>As you can see, up to 17% of people with CD have an &#8220;undefined neurological disorder&#8221;.  But even that alarmingly high statistic only accounts for people with <strong>diagnosed</strong> CD.  We know that only 1 in 8 people with CD are diagnosed.  We also know that those with CD represent only a small fraction of the population of people with gluten intolerance.  With this in mind, it&#8217;s not hard to imagine that the number of people with gluten intolerance that have &#8220;undefined neurological disorders&#8221; (and other associated conditions on the list above) could be significantly higher than current research suggests.</p>
<p>Finally, we also now know that when you are gluten intolerant &#8211; which 33% (if not more) of you are &#8211; you will also &#8220;cross-react&#8221; with other foods that have a similar &#8220;molecular signature&#8221; to gluten and its components.  Unfortunately, the list of these foods (shown below) contains all grains, which is why some medical practitioners (myself included) recommend not just a gluten-free diet, but an entirely grain-free diet.  As you can see, it also contains other foods like dairy (alpha &#038; beta casein, casomorphin, milk butyrophilin) and coffee (which is a very common cross-reactant).  </p>
<ul>
<li>alpha-caesin</li>
<li>beta-caesin</li>
<li>casomorphin</li>
<li>milk butyrophilin</li>
<li>cow&#8217;s milk</li>
<li>american cheese</li>
<li>chocolate</li>
<li>coffee</li>
<li>all cereal grains</li>
<li>quinoa</li>
<li>amaranth</li>
<li>buckwheat</li>
<li>tapioca</li>
<li>rice</li>
<li>potato</li>
<li>corn</li>
<li>sesame</li>
</ul>
<h3>Industrial seed oils: unnatural and unfit for human consumption</h3>
<p>Industrial seed oils (corn, cottonseed, soybean, safflower, sunflower, etc.) have not been a part of the human diet up until relatively recently, when misguided groups like the AHA and the ADA started promoting them as &#8220;heart-healthy&#8221; alternatives to saturated fat.</p>
<p>The graph below shows how dramatically seed oil consumption has risen over the past several decades:</p>
<p><img class="imageleft" src="http://chriskresser.chriskresserlac.netdna-cdn.com/images/pufaconsumption.png" alt="pufaconsumption" /></p>
<p>Throughout 4-5 million years of hominid evolution, diets were abundant in seafood and other sources of omega-3 long chain fatty acids (EPA &#038; DHA), but relatively low in omega-6 seed oils.  </p>
<p>Anthropological <a href="http://www.ajcn.org/cgi/content/full/71/1/179S?ijkey=5c7af875f3dc71a303f7df78c52145e8b7c31643">research</a> suggests that our hunter-gatherer ancestors consumed omega-6 and omega-3 fats in a ratio of roughly 1:1.  It also <a href="http://donmatesz.blogspot.com/2010/02/paleo-life-expectancy.html">indicates</a> that both ancient and modern hunter-gatherers were free of the modern inflammatory diseases, like heart disease, cancer, and diabetes, that are the primary causes of death and morbidity today.</p>
<p>At the onset of the industrial revolution (about 140 years ago), there was a marked shift in the ratio of n-6 to n-3 fatty acids in the diet.  Consumption of n-6 fats <a href="http://agris.fao.org/agris-search/search/display.do?f=./1989/v1507/US8845581.xml;US8845581">increased</a> at the expense of n-3 fats. This change was due to both the advent of the modern vegetable oil industry and the increased use of cereal grains as feed for domestic livestock (which in turn altered the fatty acid profile of meat that humans consumed).</p>
<p>The following chart lists the omega-6 and omega-3 content of various vegetable oils and foods:</p>
<p><img class="imageblock" src="http://chriskresser.chriskresserlac.netdna-cdn.com/images/efacontentoils.png" alt="efa content of oils" /></p>
<p>Vegetable oil consumption rose dramatically between the beginning and end of the 20th century, and this had an entirely predictable effect on the ratio of omega-6 to omega-3 fats in the American diet.  Between 1935 and 1939, the ratio of n-6 to n-3 fatty acids was <a href="http://www.ajcn.org/cgi/content/full/71/1/179S?ijkey=5c7af875f3dc71a303f7df78c52145e8b7c31643">reported</a> to be 8.4:1.  From 1935 to 1985, this ratio increased to 10.3:1 (a 23% increase).  Other calculations put the ratio as high as 12.4:1 in 1985.  Today, estimates of the ratio range from an average of 10:1 to 20:1, with a ratio <a href="http://www.ncbi.nlm.nih.gov/pubmed/19022225">as high as 25:1</a> in some individuals.</p>
<p>In fact, Americans now get almost 20% of their calories from a single food source &#8211; soybean oil &#8211; with almost 9% of all calories from the omega-6 fat linoleic acid (LA) alone! (<a href="http://www.cnpp.usda.gov/publications/foodsupply/foodsupply1909-2004report.pdf">PDF</a>)</p>
<p>This reveals that our average intake of n-6 fatty acids is between 10 and 25 times higher than evolutionary norms.  The consequences of this dramatic shift cannot be underestimated.</p>
<p>So what are the consequences to human health of an n-6:n-3 ratio that is up to 25 times higher than it should be?</p>
<p>The short answer is that elevated n-6 intakes are associated with an <a href="http://www.ajcn.org/cgi/content/abstract/83/6/S1483">increase in all inflammatory diseases</a> &#8211; which is to say virtually all diseases.  The list includes (but isn&#8217;t limited to):</p>
<ul>
<li>cardiovascular disease</li>
<li>type 2 diabetes</li>
<li>obesity</li>
<li>metabolic syndrome</li>
<li>irritable bowel syndrome &#038; inflammatory bowel disease</li>
<li>macular degeneration</li>
<li>rheumatoid arthritis</li>
<li>asthma</li>
<li>cancer</li>
<li>psychiatric disorders</li>
<li>autoimmune diseases</li>
</ul>
<p>The relationship between intake n-6 fats and cardiovascular mortality is particularly striking.  The following chart, from an article entitled <a href="http://wholehealthsource.blogspot.com/2009/05/eicosanoids-and-ischemic-heart-disease.html">Eicosanoids and Ischemic Heart Disease</a> by Stephan Guyenet, clearly illustrates the correlation between a rising intake of n-6 and increased mortality from heart disease:</p>
<p><img class="imageblock" src="http://chriskresser.chriskresserlac.netdna-cdn.com/images/hufa.jpg" alt="landis graph of hufa and mortality" /></p>
<p>As you can see, the USA is right up there at the top with the highest intake of n-6 fat and the greatest risk of death from heart disease.</p>
<p>On the other hand, several clinical studies have <a href="http://www.ncbi.nlm.nih.gov/pubmed/19022225">shown</a> that decreasing the n-6:n-3 ratio protects against chronic, degenerative diseases.  One study showed that replacing corn oil with olive oil and canola oil to reach an n-6:n-3 ratio of 4:1 led to a <a href="http://content.onlinejacc.org/cgi/content/short/47/10/2130">70% decrease</a> in total mortality.  That is no small difference. </p>
<p>Joseph Hibbeln, a researcher at the <em>National Institute of Health</em> (NIH) who has published several papers on n-3 and n-6 intakes, didn&#8217;t mince words when he commented on the rising intake of n-6 in a recent <a href="http://www.ncbi.nlm.nih.gov/pubmed/19022225">paper</a>:</p>
<blockquote><p>The increases in world LA consumption over the past century may be considered a very large uncontrolled experiment that may have contributed to increased societal burdens of aggression, depression and cardiovascular mortality. </p></blockquote>
<p>And those are just the conditions we have the strongest evidence for.  It&#8217;s likely that the increase in n-6 consumption has played an equally significant role in the rise of nearly every inflammatory disease.  Since it is now known that inflammation is involved in nearly all diseases, including obesity and metabolic syndrome, it&#8217;s hard to overstate the negative effects of too much omega-6 fat.</p>
<h3>Sugar: the sweetest way to wreck your health</h3>
<p>About 20 years ago, Nancy Appleton, PhD, began researching all of the ways in which sugar destroys our health.  Over the years the list has continuously expanded, and now includes 141 points.  Here&#8217;s just a small sampling (the entire list can be <a href="http://nancyappleton.com/141-reasons-sugar-ruins-your-health/" target="_blank">found on her blog</a>).</p>
<ul>
<li>Sugar feeds cancer cells and has been connected with the development of cancer of the breast, ovaries, prostate, rectum, pancreas, lung, gallbladder and stomach.</li>
<li>Sugar can increase fasting levels of glucose and can cause reactive hypoglycemia.</li>
<li>Sugar can cause many problems with the gastrointestinal tract, including an acidic digestive tract, indigestion, malabsorption in patients with functional bowel disease, increased risk of Crohn’s disease and ulcerative colitis.</li>
<li>Sugar can interfere with your absorption of protein.</li>
<li>Sugar can cause food allergies.</li>
<li>Sugar contributes to obesity.</li>
</ul>
<p>But not all sugar is created alike.  White table sugar (sucrose) is composed of two sugars: glucose and fructose.  Glucose is an important nutrient in our bodies and is healthy, as long as it&#8217;s consumed in moderation.  Fructose is a different story.</p>
<p>Fructose is found primarily in fruits and vegetables, and sweeteners like sugar and high-fructose corn syrup (HFCS).  A recent USDA report <a href="http://www.usda.gov/factbook/chapter2.pdf">found that the average American eats 152 pounds of sugar each year</a>, including almost 64 pounds of HFCS.</p>
<p>Unlike glucose, which is rapidly absorbed into the bloodstream and taken up by the cells, fructose is shunted directly to the liver where it is converted to fat.  Excess fructose consumption causes a condition called non-alcoholic fatty liver disease (NAFLD), which is <a href="http://www.ncbi.nlm.nih.gov/pubmed/17690317?dopt=AbstractPlus&#038;holding=f1000,f1000m,isrctn">directly linked to both diabetes and obesity</a>. </p>
<p>A 2009 study showed that shifting 25% of dietary calories from <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673878/">glucose to fructose caused a 4-fold increase in abdominal fat</a>.  Abdominal fat is an <a href="">independent predictor</a> of insulin sensitivity, impaired glucose tolerance, high blood pressure, high cholesterol, high triglycerides and several other metabolic diseases.</p>
<p>In a <a href="http://www.youtube.com/watch?v=dBnniua6-oM&#038;hd=1">widely popular talk on YouTube</a>, Dr. Robert H. Lustig explains that fructose has all of the qualities of a <strong>poison</strong>.  It causes damage, provides no benefit and is sent directly to the liver to be detoxified so that it doesn&#8217;t harm the body.</p>
<p>For more on the toxic effects of fructose, see <a href="http://perfecthealthdiet.com/?page_id=8">The Perfect Health Diet</a> and Robert Lustig&#8217;s YouTube talk: <a href="http://www.youtube.com/watch?v=dBnniua6-oM&#038;hd=1">Sugar, The Bitter Truth</a>. </p>
<h3>Soy: another toxin promoted as a health food</h3>
<p>Like cereal grains, soy is another toxin often promoted as a health food.  It&#8217;s now ubiquitous in the modern diet, present in just about every  packaged and processed food in the form of soy protein isolate, soy flour, soy lecithin and soybean oil.  </p>
<p>For this reason, most people are unaware of how much soy they consume.  You don&#8217;t have to be a tofu-loving hippie to eat a lot of soy.  In fact, the average American &#8211; who is most definitely not a tofu-loving hippie &#8211; gets up to 9% of total calories from soybean oil alone.</p>
<p>Whenever I mention the dangers of soy in my public talks, someone always protests that soy can&#8217;t be unhealthy because it&#8217;s been consumed safely in Asia for thousands of years.  There are several reasons why this isn&#8217;t a valid argument.  </p>
<p>First, the soy products consumed traditionally in Asia were typically fermented and unprocessed &#8211; including tempeh, miso, natto and tamari.  This is important because the fermentation process partially neutralizes the toxins in soybeans.</p>
<p>Second, Asians consumed soy foods as a condiment, not as a replacement for animal foods.  The average consumption of soy foods in China is 10 grams (about 2 teaspoons) per day and is 30 to 60 grams in Japan.  These are not large amounts of soy.</p>
<p>Contrast this with the U.S. and other western countries, where almost all of the soy consumed is highly processed and unfermented, and eaten in much larger amounts than in Asia.</p>
<p>How does soy impact our health?  The following is just a partial list:</p>
<ul>
<li>Soy contains trypsin inhibitors that inhibit protein digestion and affect pancreatic function;</li>
<li>Soy contains phytic acid, which reduces absorption of minerals like calcium, magnesium, copper, iron and zinc;</li>
<li>Soy increases our requirement for vitamin D, which 50% of American are already deficient in;</li>
<li>Soy phytoestrogens disrupt endocrine function and have the potential to cause infertility and to promote breast cancer in adult women.</li>
<li>Vitamin B12 analogs in soy are not absorbed and actually increase the body’s requirement for B12;</li>
<li>Processing of soy protein results in the formation of toxic lysinoalanine and highly carcinogenic nitrosamines;</li>
<li>Free glutamic acid or MSG, a potent neurotoxin, is formed during soy food processing and additional amounts are added to many soy foods to mask soy’s unpleasant taste; and,</li>
<li>Soy can stimulate the growth of estrogen-dependent tumors and cause thyroid problems, especially in women.</li>
</ul>
<p>Perhaps most alarmingly, a <a href="http://humrep.oxfordjournals.org/content/23/11/2584.full" target="_blank">study at the Harvard Public School of Health</a> in 2008 found that men who consumed the equivalent of one cup of soy milk per day had a 50% lower sperm count than men who didn&#8217;t eat soy.  </p>
<p>In 1992, the Swiss Health Service estimated that women consuming the equivalent of two cups of soy milk per day provides the estrogenic equivalent of one birth control pill.  That means women eating cereal with soy milk and drinking a soy latte each day are effectively getting the same estrogen effect as if they were taking a birth control pill.</p>
<p>This effect is even more dramatic in infants fed soy formula.  Babies fed soy-based formula have 13,000 to 22,000 times more estrogen compounds in their blood than babies fed milk-based formula. Infants exclusively fed soy formula receive the estrogenic equivalent (based on body weight) of at least five birth control pills per day.</p>
<p><a href="http://www.westonaprice.org/soy-alert/667-studies-showing-adverse-effects-of-soy.html" target="_blank">Click here </a>for a complete list of studies demonstrating the harmful effects of soy products.</p>
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		<title>Soy foods associated with lower sperm counts</title>
		<link>http://chriskresser.com/soy-foods-associated-with-lower-sperm-counts</link>
		<comments>http://chriskresser.com/soy-foods-associated-with-lower-sperm-counts#comments</comments>
		<pubDate>Tue, 29 Jul 2008 16:39:21 +0000</pubDate>
		<dc:creator>Chris Kresser</dc:creator>
				<category><![CDATA[Fertility, Pregnancy & Childbirth]]></category>
		<category><![CDATA[Food & Nutrition]]></category>
		<category><![CDATA[fertility]]></category>
		<category><![CDATA[infertility]]></category>
		<category><![CDATA[male]]></category>
		<category><![CDATA[men]]></category>
		<category><![CDATA[soy]]></category>
		<category><![CDATA[sperm]]></category>

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		<description><![CDATA[A recent, large study published in Human Reproduction has demonstrated that soy products are associated with dramatic reductions in sperm counts.]]></description>
			<content:encoded><![CDATA[<p></p><p><img class="imageleft" src="http://chriskresser.chriskresserlac.netdna-cdn.com/images/tofu.png" alt="tofu meal" />A <a href="http://humrep.oxfordjournals.org/cgi/content/abstract/den243v1">study</a> recently published in <em>Human Reproduction</em> demonstrated that intake of soy foods significantly reduces sperm counts in men.</p>
<p>The study is especially significant because it is the largest study in humans to examine the relationship between semen quality and phytoestrogens (plant compounds that can mimic the physiological effects of the endogenous hormone, estrogen).</p>
<p>Dr. Jorge Chavarro of the Harvard School of Public Health and his colleagues found that men who ate the most soy food had 41 million sperm per milliliter less than men who did not consume soy products.  The normal sperm concentrations for men ranges between 80 and 120 million/ml.</p>
<p>The association between soy food intake and sperm concentrations was even stronger in men who were overweight or obese, and 72% of study participants were.  They also found the relationship between soy foods and sperm concentration was strongest in men with &#8220;normal or high&#8221; sperm counts.</p>
<p>Animal studies have linked the high consumption of isoflavones with infertility, but until now there has been little evidence of this effect in humans.  Isoflavones are plant compounds with estrogen like effects and are found mainly in soybeans and soy-derived products.</p>
<p>What is particularly revealing is that the men in the highest intake group (who had the largest sperm count reduction) had a mean soy food intake of <em>only half a serving per day.</em>  This is equivalent to having one cup of soy milk or one serving of tofu, tempeh or soy burgers <em>every other day!</em></p>
<p>I don&#8217;t know about you, but I happen to know quite a few people who consume a lot more soy than than that on a regular basis.  Sadly, many of them are children whose parents innocently believe that soy products are &#8220;healthy&#8221;.  This is not their fault, of course; this erroneous and dangerous message has been aggressively promoted in the mainstream media for decades.</p>
<p>If the effect of such moderate servings of soy on adult males is so significant, what effect might soy foods have on developing boys who have not yet reached sexual maturity?</p>
<p>&#8220;Early puberty (caused by consuming soy products) may increase a boy&#8217;s chances of developing testicular cancer later in life, because it means longer exposure to sex hormones,&#8221; said University of North Carolina researcher Marcia Herman-Giddens. Congenital abnormalities of male genital tracts are also increasing. Recent studies found a higher incidence of birth defects in male offspring of vegetarian, soy-consuming mothers.</p>
<p>What about babies?  Preliminary studies indicate that children given soy formula go through puberty much earlier than children who were not fed soy products.  A 1994 study done in New Zealand revealed that, depending on age, potency of the product, and feeding methods, infants on soy formula might be consuming the equivalent of up to 10 contraceptive pills a day. By exposing your baby to such large amounts of hormonal-like substance, you are risking permanent endocrine system damage (pituitary gland, pineal gland, hypothalamus, thyroid, thymus gland, pancreas, ovary, testis, adrenal glands).</p>
<p>Dr Chavarro speculates that the increased estrogenic activity caused by consumption of soy foods may have an adverse effect on the production of sperm by interfering with other hormonal signals. This effect could be strengthened further in overweight and obese men because men with high levels of body fat produce more oestrogen than slimmer men, leading to high overall levels of oestrogen in the body and reproductive organs.</p>
<p>If you&#8217;re wondering how soy continues to be so widely accepted and aggressively promoted as a &#8220;health food&#8221; in spite of the overwhelming evidence to the contrary, I recommend reading <a href="http://www.amazon.com/Whole-Soy-Story-Americas-Favorite/dp/0967089751/ref=pd_bbs_sr_1?ie=UTF8&#038;s=books&#038;qid=1217348458&#038;sr=8-1">The Whole Soy Story</a> by Kaayla Daniel, PhD, CCN.  You can read introduction to this eye-opening book <a href="http://www.westonaprice.org/soy/promotion.html">here</a>.</p>
<p>The history of soy products and their designation as a &#8220;health food&#8221; is particularly revealing, as Daniel points out:</p>
<div class="insert">
<p>Early soy food promotion in America aimed at two specific markets—vegetarians and the poor—soy milk and soy cereals for Seventh Day Adventists, Bac-O-Bits and meat extenders for the budget conscious. But there was a lot of soy to sell and these markets were limited. There was so much to sell because the market for processed foods had experienced explosive growth since the 1950s—and most processed foods contain soy oil. The industry found itself saddled with a waste problem, the leftover sludge from soy-oil manufacture which it could either dump or promote. The exigencies of corporate life naturally chose profit-seeking over disposal and that meant expanding the market, finding more ways to use soy ingredients in processing and convincing more people to pay money for soy-based imitation foods.</p>
<p>&#8220;The quickest way to gain product acceptability in the less affluent society,&#8221; said a soy-industry spokesperson back in 1975, &#8220;. . . is to have the product consumed on its own merit in a more affluent society.&#8221; Thus began the campaign to sell soy products to the upscale consumer, not as a cheap poverty food, but as a miracle substance that would prevent heart disease and cancer, whisk away hot flashes, build strong bones and keep us forever young. Soy funds for research enlisted the voices of university professors who haplessly demonized the competition—meat, milk, cheese, butter and eggs.</p>
</div>
<p>Soy is one of the &#8220;Big Four&#8221; cash crops in the U.S. and the funds for its marketing are enormous:</p>
<div class="insert">
<p>&#8220;Farmers pay a fee for every bushel of soybeans they sell and a portion of every dollar spent on Twinkies, TV dinners and the thousands of other processed foods that contain soy in one form or another, ultimately go towards the promotion of the most highly processed foods of all—imitation meat, milk, cream, cheese, yogurt, ice cream, candy bars and smoothies made from soy.</p>
<p>All soybean producers pay a mandatory assessment of one-half to one percent of the net market price of soybeans. The total—something like eighty million dollars annually—supports United Soybean’s program to &#8220;strengthen the position of soybeans in the market place and maintain and expand domestic and foreign markets for uses for soybeans and soybean products.&#8221;</p>
</div>
<p>And of course, these advertising dollars are largely responsible for creating the erroneous notion that highly processed soy foods are &#8220;healthy&#8221;:</p>
<div class="insert">
<p>&#8220;A survey of March 2004 health magazines reveals five-and-one-half pages of ads for products containing soy in Alternative Medicine (two of which promote soy as a solution to the problems of menopause); five-and-one-half pages in Vegetarian Times; and five pages in Yoga Journal. The ads that keep today’s health-oriented publications afloat aim at mainstream, not alternative, culture: soy milk ads feature faces of smiling children; high-protein bars create expressions of ecstacy on upside-down models; and a hostess who serves chocolate-covered soy nuts is the toast of her party.&#8221;</p>
</div>
<p>However, in spite of advertising and popular belief, processed soy products are not health foods.  Because of their estrogenic effects, they act more like drugs in the body than foods.  And as we all know, drugs can be extremely dangerous when taken irresponsibly and without indication.  Millions of men, women and children around the world are &#8220;drugging&#8221; themselves daily with soy products, and the tragic irony is that this is done in the name of &#8220;health&#8221;.</p>
<p>Keep in mind that tofu, tempeh and soy milk are not the only sources of soy.  In fact, almost all processed food has soy in it, in the form of soy oil, soy lecithin, soy flour or soy protein.  Everything from your favorite corn chips to hamburger buns to mayonnaise is likely to contain a substantial amount of soy.</p>
<p>The most sensible approach, then, is to eliminate processed soy products from your diet and dramatically reduce or eliminate your consumption of processed food (of course there are many other reasons to do this &#8211; soy is just one).</p>
<p>A small amount of miso or natto or other fermented soy product as a condiment every now and then is probably not harmful.  But those are not the soy products Americans tend to eat.</p>
<p>For more information about the dangers of soy products, please see my recent article called <a href="http://chriskresser.com/the-soy-ploy/">The Soy Ploy</a>.</p>
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		<title>The Soy Ploy</title>
		<link>http://chriskresser.com/the-soy-ploy</link>
		<comments>http://chriskresser.com/the-soy-ploy#comments</comments>
		<pubDate>Fri, 30 May 2008 14:47:10 +0000</pubDate>
		<dc:creator>Chris Kresser</dc:creator>
				<category><![CDATA[Babies & Kids]]></category>
		<category><![CDATA[Food & Nutrition]]></category>
		<category><![CDATA[Myths & Truths]]></category>
		<category><![CDATA[children]]></category>
		<category><![CDATA[estrogen]]></category>
		<category><![CDATA[formula]]></category>
		<category><![CDATA[isoflavones]]></category>
		<category><![CDATA[isolate]]></category>
		<category><![CDATA[ploy]]></category>
		<category><![CDATA[protein]]></category>
		<category><![CDATA[soy]]></category>

		<guid isPermaLink="false">http://chriskresser.com/?p=38</guid>
		<description><![CDATA[Although widely promoted as a health food, hundreds of studies link modern processed soy to malnutrition, digestive problems, thyroid dysfunction, cognitive decline, reproductive disorders, immune system breakdown, and even heart disease and cancer.]]></description>
			<content:encoded><![CDATA[<p></p><div class="insert">
<p>Today&#8217;s article about the dangers of soy products is from <a href="http://www.nourishingourchildren.org/">Nourishing Our Children</a>, an organization dedicated to supported learning, behavior and health in children through optimal nutrition.  I encourage all parents to visit their website and read the &#8220;What Parents Need to Know&#8221; section. There is also a <a href="http://www.nourishingourchildren.org/offerings/downloads.html">downloads</a> section with free guides and briefing books available for download.</div>
<p><img class="imageleft" alt="soybeans" src="http://chriskresser.chriskresserlac.netdna-cdn.com/images/soybeans.jpg" />Although widely promoted as a health food, hundreds of studies link modern processed soy to malnutrition, digestive problems, thyroid dysfunction, cognitive decline, reproductive disorders, immune system breakdown, and even heart disease and cancer. How could soy be linked to all this disease?  Because the soybean contains many naturally occurring toxins.  All legumes contain toxins but the problem with soy is that the toxins are found in very high levels and are resistant to the traditional ways of getting rid of them.</p>
<p>Long, slow fermentation (as in the traditional production of miso, tempeh and soy sauce) gets rid of the phytic acid and other digestive inhibitors but not the phytoestrogens in soy.</p>
<h3>Myths About Isoflavones </h3>
<p>One of the most common myths is that soy estrogens (isoflavones) are beneficial for your health. Isoflavones are the estrogen-like compounds occurring naturally in soy foods.  They act as the plant’s natural pesticides, causing insects to become sterile. Research has shown that isoflavones can prevent ovulation and stimulate the growth of cancer cells.  As little as 38 mg isoflavones per day (less than the amount found in 1 cup of soy milk) can result in hypothyroidism with symptoms of lethargy, constipation, weight gain and fatigue. The isoflavones in soy have been shown to cause reproductive problems, infertility, thyroid disease and liver disease in mice, rats, cheetahs, sturgeon, quail, sheep, pigs and marmoset monkeys.</p>
<h3>Traditional Versus Modern Soy Foods </h3>
<p>It is important to distinguish between traditional and modern soy foods. In Asia, traditional soy foods were consumed in small amounts, usually as a fermented condiment.  Traditional fermented soy foods include miso, soy sauce, tempeh and natto. Tofu was prepared by a precipitation process that gets rid of some of the anti-nutrients, and tofu was often then fermented. Tofu was usually consumed in small amounts in fish broth, which provided lots of compensating minerals and compounds that support thyroid function.</p>
<p>Soymilk underwent a very long preparation process to get rid of anti-nutrients and it was consumed with shrimp or egg yolk, ingredients that helped compensate for the many anti-nutrients that remained. Mostly a food for the elderly, it was sometimes given to nursing mothers but never to growing children.</p>
<h3>Problems with Soy Protein Isolate </h3>
<p>Modern soy foods are very different.  Most are made with soy protein isolate (SPI), which is a protein-rich powder extracted by an industrial process from the waste product of soy oil manufacturing. It is the industry’s way of making a profit on a waste product.  The industry spent over 30 years and billions of dollars developing SPI.</p>
<p>Soy Protein Isolate is produced at very high temperatures and pressures. This processing does get rid of some of the anti-nutrients in soybeans, but unfortunately many of the proteins are denatured in the process, including lysine.  That is why growing animals fed soy must be given a lysine supplement. In feeding studies, SPI caused many deficiencies in rats.  That soy causes deficiencies in B12 and zinc is widely recognized; but the range of deficiencies was surprising.</p>
<p>Although SPI is added to many foods, it was never granted GRAS status, meaning “Generally Recognized as Safe”.  The FDA only granted GRAS status to SPI for use as a binder in cardboard boxes. During the processing of soy, many additional toxins are formed, including nitrates (which are carcinogens) and a toxin called lysinoalanine.  It was concerns about lysinoalanine in SPI that led the FDA to deny GRAS status for SPI as a food additive.</p>
<p>In spite of all these problems, SPI is the basic ingredient of soy infant formula and the FDA even allows a health claim for foods containing 6.25 grams SPI per serving.</p>
<h3>The Dangers of Soy Infant Formula </h3>
<p>Infants on soy formula can take in dangerously high levels of soy isoflavones. On a body weight basis, this can mean ten times the level that can cause thyroid suppression in adults after three months, and eight times the level that can cause hormonal changes in adults after just one month.</p>
<p>According to a Swiss report adult women consuming 100 mg isoflavones (about 2 cups of soy milk, or 1 cup of cooked mature soybeans) provide the <ahref="http://www.westonaprice.org/soy/birthcontrolbabies.html">estrogenic equivalent of a contraceptive pill</a>.</p>
<p>This means for a baby that weighs 6 kg (or just over 13 pounds), 10 mg provides the estrogenic equivalent of a contraceptive pill. Thus, the average amount of soy-based formula taken in by a child provides the estrogenic equivalent of at least four birth control pills. Because babies are more vulnerable than adults to the effects of dietary estrogens, the effects could actually be much greater than that of four birth control pills.</p>
<p>Hence the statement, <em>&#8220;Babies on soy formula receive the estrogenic equivalent of at least five birth control pills per day.&#8221;</em></p>
<h3>Homemade Baby Formula </h3>
<p>For adopted infants, or as a solution for mothers who aren’t physically able to breastfeed or who aren’t able to produce enough milk, we’d like parents to know that there are nutrient dense, homemade <a href="http://www.westonaprice.org/children/recipes.html">Baby Formula Recipes</a> in the book <a href="http://www.amazon.com/Nourishing-Traditions-Challenges-Politically-Dictocrats/dp/0967089735/ref=pd_bbs_sr_1?ie=UTF8&#038;s=books&#038;qid=1212157469&#038;sr=8-1">Nourishing Traditions</a> which have been used with great success by parents all over the world since 1995!</p>
<div class="insert">
<h3>Recommended Links</h3>
<ul>
<li><a href="http://www.nourishingourchildren.org/">Nourishing Our Childre</a>n</li>
<li><a href="http://www.westonaprice.org/mythstruths/mtsoy.html">Myths and Truths About Soy</a></li>
<li><a href="http://www.westonaprice.org/soy/index.html">Soy Alert</a></li>
</ul>
</div>
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