The Roundup - Edition 14

The Roundup


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Here is The Roundup, Edition 14, bringing you the best from around the web from the past two weeks!

Blast from the Past

A great study was just published illustrating the gut-skin-immune connection and the ability of probiotics to influence that axis. The authors discuss the vicious cycle of inflammatory gut disease, where inflammation leads to leaky gut, which leads to more inflammation, and so on. The inflammatory cytokines produced by this inflammation in the gut can trigger a whole host of different skin conditions, including eczema and other allergic skin diseases.

As many of you know, the gut-skin-axis is a special interest of mine. I recorded a podcast back in December of 2011 describing how the gut-skin axis contributes to skin conditions like acne (vulgaris and rosacea), psoriasis, eczema, dermatitis and others. In November of 2012, I gave a presentation at the Weston A. Price Foundation annual conference on the gut-skin connection, and even wrote an accompanying article describing the most recent research on the topic. In my series on Nutrition for Healthy Skin, I explained how probiotics can be an important tool in treating skin conditions, provided the appropriate precautions are taken when choosing a probiotic product.

I’ve had many patients who struggle with skin problems such as acne, rosacea, and eczema, and I’ve been pleased to see how many of them have been able to significantly improve the health of their skin by changing their diet to a more gut-supportive approach. While most conventional health professionals treat problem skin with antibiotics and medication, I believe the future of skin care will pay far more attention to the patient’s gut health and to encouraging a diet that supports a healthy gut barrier and microbiome.

Research Report

  • This study explains why I’ve been encouraging people to think of probiotics as immune regulators as much as gut support.
  • New research suggests that Gymnema (an herb used for blood sugar control) kills Candida & disrupts biofilms.
  • An interesting comment on recent low-dose naltrexone study speculates that autism and M.S. may share a common cause: high levels of inducible nitric oxide synthase (iNOS) in the brain.
  • Research demonstrates that H. pylori suppresses natural immunity and increases the risk of other infections and cancer.
  • A new study elaborates on how antibiotics increase the risk the risk of gut infections.

Worth a Look

  • Free the Animal explores how resistant starch improves insulin sensitivity.
  • The Wall Street Journal examines how stress and anxiety propel us to eat more.
  • The New York Times discusses research that suggests that intense exercise leads to a short-term suppression of food intake and reduction in appetite.
  • Jill Carnahan, MD explains how gut permeability impacts a wide range of health conditions, including cancer, autoimmune disease, inflammation, and food sensitivities.

For the Foodies

  1. Chris-
    I know you don’t have time to respond often but I thought I would give it a try-or if anyone else has knowledge that would be great too. I have MS and have been on LDN for 4 years with good success. I also am homozygous (two 677T’s for MTHFR). Research shows that most kids with autism have MTHFR (Amy Yasko) and I have read about nitric oxide issues with MTHFR. Wouldn’t this study if it’s correct link MTHFR to MS? I realize my scientific understanding is limited but I am curious. My neurologist is finally coming around to LDN after seeing improvement in patients who went downhill on the common MS drugs. However, I felt a hidden rolling of the eyes from him when I mentioned my MTHFR status.

  2. Chris,

    Thank you for providing the link to the article on Gymnema as a potential treatment for candida overgrowth. I have stated before that there are a lot of people out there who could greatly benefit from a Chris Kresser scientific review and analysis of candida overgrowth and ways of accurately diagnosing and then treating this problem.

    One of the interesting things I’ve come across in my own research is how candida competes for CoQ10 in the body, meaning that supplementing this coenzyme, or eating foods rich in it, may be a double-edged sword.

    Appreciate it if you find the time to have a look – I know you are a busy man!

    Many thanks

  3. Hi Chris,

    Thanks for the interesting article and valuable information.
    Do you think these food sensitivities and gut permeability you address here can cause weak, fine hair that breaks off and dwindles off into nothing after it’s a few inches long? My hair gets worse and worse; it doesn’t seem to matter how careful I am.

    Thanks for your help!

  4. Does anyone know what is the typical bacterial composition of grass-fed bovine milk?
    Are these bacteria capable of colonizing the human gut?

  5. Chris, any further studies on Gymnema in terms of which Candida infections it treats, what stage of infection it needs to be started, how long to take it, etc.? It looks promising, but the details are sketchy at best and I hate to waste money chasing the latest hot supplement without clearer indications and objectives.