UTIs can be caused by poor hygiene, impaired immune function, the overuse of antibiotics, the use of spermicides, and sexual intercourse. The most common cause, accounting for about 90 percent of all cases, is the transfer of Escherichia coli bacteria from the intestinal tract to the urinary tract.
For those of you who have experienced a UTI, there isn’t much you wouldn’t do to avoid another one. While I personally have never had a UTI, my patients have told me how symptoms like pain, burning, nausea, and even bloody urine can be debilitating, and for those who get chronic UTIs, the fear of infection can be enough to prevent engagement in any activities that could trigger one. For people who get them frequently, sometimes a specific cause cannot even be pinpointed. This can be frustrating and scary.
Fortunately, there are a few methods of natural UTI treatment and prevention that have worked extremely well for my patients, to the point where they no longer worry about getting a UTI.
These treatments don’t require a prescription, are inexpensive, and are completely drug-free. While your doctor may not know about them, I hope this article will help you completely avoid UTIs—or at least significantly reduce their frequency and severity. I recommend working with a Functional Medicine practitioner who is focused on treating the root cause of your UTIs.
UTIs can be debilitating, but it is possible to get relief without requiring a prescription. Check out this article for five ways to cure UTIs without antibiotics. #functionalmedicine #wellness #chriskresser
What Is the Standard Treatment for a UTI?
Doctors typically use antibiotics to treat UTIs, and the type and duration depend on your health condition and the type of bacterium found in your urine. (2) Commonly prescribed antibiotics are:
- Trimethoprim/sulfamethoxazole (Bactrim)
- Amoxicillin
- Ampicillin
- Ciprofloxacin (Cipro)
These antibiotics are often unnecessary and may cause more problems in the future by destroying the beneficial bacteria that prevent pathogenic bacteria from growing. Long-term use of antibiotics can also lead to antibiotic resistance in strains of bacteria like E. coli in the gut, and a UTI caused by these bacteria will be even more challenging to eliminate and can cause more serious issues like a kidney or bladder infection.
Furthermore, antibiotics do very little to prevent the infection from happening in the first place. So, while drugs may be an easy fix for the short term, in the long run, you will continue to be susceptible to UTIs, and these infections may be worse than if you had never taken a course of antibiotics in the first place!
Curing and Preventing UTIs Naturally: D-Mannose
Treating UTIs with D-Mannose
D-mannose is by far the most effective supplement for both treatment and prevention of UTIs. Similar to glucose in structure, D-mannose is a naturally occurring sugar that is found in a number of fruits, including apples, blueberries, and cranberries. (3) This sugar is the reason that cranberry juice has been commonly recommended as a UTI treatment, though it is far easier to get the recommended dosage from a supplement. D-mannose is effective because it attaches to E. coli bacteria, causing them to stick to each other and preventing them from sticking to the walls of the urinary tract. (4) The bacteria can then easily be eliminated from the body during urination.
D-mannose, even in large quantities, does not cause any adverse effects, and cannot be metabolized the way other sugars can, meaning this supplement is safe for people with diabetes and others who are avoiding sugar for any reason. This treatment is also safe for children and the elderly.
Symptom relief can be seen as quickly as the following day, and most symptoms of UTI are generally resolved after 48 hours of treatment. Additionally, taking D-mannose during a time where you feel you are most prone to UTIs, such as before intercourse or during prolonged antibiotic treatment, can help prevent a UTI from ever developing in the first place. This is especially helpful for those who are prone to chronic UTIs and want to be able to engage in normal life activities without fear of infection.
The typical dose of D-mannose for UTI treatment is 500 mg, in capsule or powder form, taken with or in a glass of water or juice every two to three hours for five days. It is a good practice to continue taking the supplement even after symptoms have diminished to ensure complete elimination of the bacteria in the urinary tract. This dose can also be taken as a preventive, or prophylactic, method.
While there has not been any peer-reviewed research to support the effectiveness of D-mannose in treating or preventing UTIs, clinical and anecdotal experience suggests it is highly effective for the majority of infections, both acute and chronic. Some of my patients who have used D-mannose as a UTI treatment method have even described its effects as “miraculous”—so it’s definitely worth a shot!
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Four Alternative Treatments for Chronic UTIs
One caveat with D-mannose is that it is only effective with UTIs caused by E. coli infection. While this accounts for about 90 percent of cases, 10 percent will not benefit from this treatment. In this case, supplements that help disrupt biofilms can be useful in treating and preventing UTIs.
Biofilms are an accumulation of microorganisms and their extracellular products forming structured communities attached to a surface such as the lining of the urogenital tract. (5) The development of a biofilm can make infections extremely hard to treat, since they commonly return shortly after treatment is stopped.
The antibacterial resistance of pathogenic biofilms is one of the major reasons why those who get a UTI are highly susceptible to getting more in the future—if the biofilm is not completely eliminated, the infection will eventually return at some point.
1. InterFase Plus and Biofilm Defense
This is why the use of biofilm disruptors can be helpful for preventing the recurrence of chronic UTIs. The biofilm disruptors that I recommend to my patients are InterFase Plus from Klaire Labs or Biofilm Defense from Kirkman. These contain specialized enzymes to disrupt the biofilm matrix embedding potential of pathogens, and dissolve the sugar and fibrin components of most pathogenic biofilms. By destroying the biofilms, the recurrence of UTIs despite proper hygiene can be reduced. (6)
2. Lauricidin
Lauricidin is another supplement that may help in treating UTIs, particularly those that are caused by types of bacteria other than E. coli. Lauricidin (a proprietary form of monolaurin) has antiviral, antifungal, and antibacterial activity, and is specific against pathogenic bacteria so it won’t disrupt beneficial bacteria in the gut. It is highly effective at combating gram-positive bacteria in the families of: (7)
- Streptococcus
- Staphylococcus
- Corynebacterium
- Listeria
- Bacillus
- Clostridium
It works by disturbing the integrity of the bacterial cell membrane, blocking replication and making it easier for the immune system to destroy the pathogen. Lauricidin is only helpful, however, for UTIs not caused by E. coli, which is gram-negative and has a different kind of outer cell membrane than gram-positive bacteria.
3. Nattokinase
Nattokinase is another enzyme that has been shown to dissolve biofilms. (8) Produced by the bacteria found in the fermented food natto, this enzyme is proteolytic and can help break down the fibrin proteins that maintain the structure of biofilms.
Because of its fibrin-breaking ability, it’s important that nattokinase supplements are not taken by people with bleeding disorders, or by people who are taking Coumadin (warfarin), aspirin, or any other drug that influences blood clotting, unless supervised by a physician.
4. Apolactoferrin
Apolactoferrin (or lactoferrin) is one more supplement that I recommend to my patients with recurrent UTIs. This multifunctional protein lactoferrin is a component of the immune system with antimicrobial activity, and is part of the innate defense, found mainly in secretions and mucosal surfaces. (9)
Lactoferrin has been shown to block pathogenic biofilm development by binding to iron and causing the bacteria to “wander” across surfaces instead of forming cell clusters and biofilms. (10, 11) One study found that the amount of E. coli bacteria in the kidneys and bladder of mice was significantly reduced 24 hours after oral lactoferrin treatment, compared to a control group. (12) More research is necessary to demonstrate the effectiveness of lactoferrin in treating UTIs, but I believe it is worth trying, especially if dealing with chronic UTIs.
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I have been struggling with bladder infections every since I had 4 bladder surgeries done by 4 different doctors. Over 10 years ago now. I became allergic to most antibiotics, and my bladder infections just kept returning. I was put on amoxicillin daily. I have done that for several years, but then I would get a rash from that also. I do believe there is a difference in the D-Mannose you buy. I have found the one by “now”, 500mg to work best for me. I recently started getting more bladder infections that would not go away with anything. After reading online, I decided to combine D-Mannose with Uva Ursi Bearberry, 500MG. Thank goodness it’s working. I have given up the amoxicillin, also. When I went to my doctor, he suggested I get a pic put in my arm again. That was a disaster years ago as I was allergic to the Tobramycin I was given. Terrible vertigo. I appreciate all the comments I have read on here. Thanks for sharing!
Please let me know what D-mannose 500 mg is the best and were to bay thank you.liz
Got mine today at GNC. The person working knew exactly what it was when I walked in and asked. I’m allergic to penicillin and am very hopeful this will help.
Barley water can be obtained by boiling a handful of barley in a litre of water.
Barley water is ready when barley is cooked well.
After drinking the barley water, is eating the barley going to help with my uti ? Have tried so many things as I have had uti for almost 4 weeks, antibiotics and all. Getting desperate!
Hi. I’m wondering, does anyone know… How long/often can people take the supplements recommended above? My mother has an antibiotic resistant bladder infection and there is nothing that the doctors can do but give her ridiculously strong antibiotics (which they admit might not even work.) Anyone know what kind of long term effects are associated with D-Mannose or biofilm disruptors? Thanks. 🙂
My 4 year old seems to have labial adhesion and in getting a doctors opinion on it we have been asked to give her antibiotics because they found some Bactria in a swab. I’m extremely reluctant to give antibiotics. My daughter isn’t complaining of vaginal pain (she was previously). But I don’t seem to have the support of the doctor to try anything other then antibiotics. I’m in a city with limited health services. So my plan is to find an alternative to the antibiotics and not tell the doctor and see if the next swab is normal. My question is can I try two if the above recommended supplements at once on my kid? I’m concerned about the 90/10 ratio mentioned in the article.
Thank you! Had UTIs around 4 times per year and could not bear taking another round of Cipro. Saw your advice on D-mannose. Ran to Whole Foods – it took two “emergency” strength containers but I am UTI free for 2 months. So, actually ended up being more expensive than a doctor trip and a round of antibiotics but so worth not having to use antibiotics.
Yes, that is exactly my experience, I have been plagued by UTIs & kidney infections since I was 4 yrs old, years of Antibiotics, awful, D-mannose worked like a miracle.
Doctor said to put polysporin on urethra after sex. Has anyone heard of that or tried it? He gave me a prescription for pills that numb the pain of the bladder and urethra and I’m hoping there’s no side effects apart from the orange urine.
Also the pharmacist recommended using a lube even if don’t need it as sex can cause tiny tears in the urethra.
I don’t want to take preventative anti-biotics after every time having sex but I’m at my wits end here and hopefully the above advice will work instead
Hi Alice,
I suffered for years with uti’s going from one antibiotic to another. I then had a urethane stretch and docs were saying my urine wasn’t shoeing much and that I should. … live with it!!!!
I was prescribed an anti depressant which has basically eradicated the uti ‘ s. I have a new partner and we don’t each other often. Everytime we have sex I get a raging uti within 24 hours. I am currently in bed with macrobid feeling sorry for myself and now not know if what to do really. How can I tell my new partner well actually we can’t have sex.
I reduced incidents by taking 2000-3000 units of Vit C before coitus and the morning after, followed by lots of water, pure cranberry juice and d-mannose. Also shared a shower first with lots of mutual scrubbing. When I followed this routine, infections were rare. Good luck.
I’m really excited to find your site!! I have straphylococcus saprophyticus should I be taking lauricidin? where can I get it and how much should I take? I’ve been taking d-mannose, drinking hibiscus tea and kombucha, taking probiotics and drinking lots of water. So d-mannose won’t work for this type of bacteria? Will it help at all or should I not take it?
Who ever has UTI ,first thing to do is Stop consuming SUGAR(The white poison) Immediately.
The sugar sticks to the walls of the Bladder and the bacteria like E-coli and other ,feeds on it and grows ,causing severe UTI.
Also try natural products like:
1.Drink Barley water Daily .
2.Consume spices like Cinnamon sticks and Star Anise(It kills Germs).
3.Have Cranberry Juice without any added Sugar.
Also try Homeopathy Medicines. Its natural and has no side effects.And the Homeopathic medicines reach where it has to ,to clear the infection,whereas Allopathic medicines don’t.
I am free of the UTI for almost 2 years now since I started taking all the measures mentioned above.
All the Best!!
How to get barley water, do you purchased it or is it homemade?
Barley water can be obtained by boiling a handful of barley in a litre of water.
Barley water is ready when barley is cooked well.
Does anyone know if you’re better to have acidic or alkaline urine to prevent utis? so much conflicting information online. I’ve heard that an alkaline diet is so much healthier and can prevent cancer etc. But then there’s a ton of info saying to do the opposite if you have frequent UTI’s. I’ve been drinking lemon water in the morning to help my kidney stones and now i’ve just read on a bladder website not to avoid that and alkaline foods. I’m so confused and frustrated. Also some saying cranberry is the worst thing for your bladder and then others saying to take every day. I’m going to try and take d-mannose as a preventative starting today as nothing but anti-biotics help once I get them. Usually from sex but I have different kinds of UTI’s.
alice-
I don’t know the definitive answer to your primary question, but I also drink lemon water in am and while we think of lemon as an acid, its effect is alkalinizing.
I’m 23 years old and have been suffering from uti’s over the years but it has been this past year and a half where I’ve been getting them A lot more then in the past: I feel like I go to the doctor every other week for antibiotics and then again because the antibiotics always cause me to get a yeast infection. I’ve been told I have interstitial cystitis..other Drs. Said I do NOT have I.C. I’ve gone to a urogyne who then prescribed me antibiotics (bectrim) to take after intercourse. But I haven’t because I’ve been scarred of the side effects. I HATE taking all these antibiotics/medicine. Also last year I was misdiagnosed with herpesvirus type 1 in the genital area. I did not have any of the classic symptoms other then I had what appeared like 3 paper cuts on my perineum. a year later I got them again same 3 cuts. BOTH times in which I ALSO had a uti and yeast infection from the antibiotics. I insisted on getting re tested in where the results came back NEGATIVE for the virus. My then doctor told me that the cuts where from the reoccurring uti and yeast infection making my sling dry and sensitive and ripping (3 cuts) during intercourse. It’s been about 6 months now that those cuts hve scared over and I haven’t had any problems with them anymore but I’m still suffering from these damn uti’s. I just came across this page so I will be trying these remedies out and I am crossi my fingers that they work because I’m going insane!!! As you can imagine I have lost trust in doctors. So I really hope these remedies help.
I’ll keep posted!
Thank you
Many women are unaware that hormonal changes in the body, specifically in estrogen levels can cause UTIs. Following a hysterectomy, a was plagued with one UTI after the other. My doctor was perplexed, and finally, after trying just about every natural remedy recommended to me by friends and an excruciatingly painful cystoscopy (words cannot describe…), he prescribed a long term antibiotic.
I never started that antibiotic. Instead, I went to a naturopath. She prescribed a compounded estrogen vaginal cream, Estriol-C, to be applied nightly. It has been 8 years since I have had a UTI, and I am still curious as to why other women my age (48) have not heard of this simple solution when there is an abalance of E-coli in the culture. There is growing evidence to support this. Here is just one of many articles on the topic of the low estrogen-UTI connection:
http://www.sciencedaily.com/releases/2013/06/130619164620.htm
What to do about a urea plasma. I think thats not a gram positive bacteria? I suffer from it for four years now
Can anybody tell me where I could get Estriol-C compounded in the UK. We are so far behind here!!!
where can I buy D Mannose from a licensed company
I use Estriol. You can obtain it through Amazon. Good luck.
Sandra O’Brien,
I am 48 years old and going through menapause and was prescribed Estrace by my Urologist because I have dryness, low astringent and recurring UTI’s…I was told not to use this cream topically for a couple of months and not for a long term since there can be a risk of cancer….I have also been seeing a an Osteopathic dr who also practices Integrative medicine an d deals with hormonal balance and he suggested that I try the BIEST cream from a compounding pharmacy and that it’s safer to use
than the Estrace cream ….I am still skeptical and would like to know what cream is safe to use in a long term with out worrying about cancer? The difference between Estrace cream is that it has Estradiol and the Biest cream has Estradiol and Estriol…is the cream Estriol-C that was prescribed by your naturoparh safe to use for a long term and there is no risk of cancer?
Note: I myself like to use a natural approach that works and don’t care to use antibiotics tha can have bad side affect.
Sandra,
There is a typo on my post dated 3/20/15… I meant to say that I was told by my Urologist to use the Estrace cream topically for 2-months which I did and not to use it for a long term…I also started using for prevention a supplement D-Mannose with CranActin from Solaray to see if that will help me to prevent UTI’s…my condition is related to menopause due to low estrogen and would like to consider a natural product that will work for me without worrying about bad side affects…I am also using the Progesta cream for topical use for my hormonal imbalance to help me with anxiety and hot flashes…
My aunt who has had chronic Uti’s now drinks 2 quarts of water a day and no longer gets them. She was on antibiotics off and on for 6 months before a urologist told her to drink this amount of water. She wondered why the doctors didn’t tell her this instead of continuing to give her antibiotics.
The last time I got a uti I tried echinacea – goldenseal tincture by Herb pharmacy and low and behold to my amazement it worked! So grateful because when I get one I am in extreme pain and it comes on very quickly.
Use to have recurring UTI infections whilst detoxing vigorously, treat them with anti-biotics for the first time then the last time I had it I took 10 tbsps of amla/Indian Gooseberry powder (which is rich in Vitamin C, has 10 times more Vitamin C than oranges), a high dose of Vitamin C between 2000-8000 mg with cranberry juice. Uti gone and hasn’t returned for a year now. Hope that helps anyone out there,
I am not a doctor but this is what my specialist told me. there are numerous reasons for uti. for women it is so commonly e coli , or fecal matter, which has made its way near the urithera and the germs have spread to the warmth of your bladder and spread like nuts. To my distress, as a woman who was taught how to properly whipe her ass, I have dealt with re-occuring UTIS which are drug resistant because they are not caused by E coli and because they are reoccuring. the specialist inspected my bladder and noticed that it was “distended”. this means that my bladder was englarged. infact it was twice the size of normal bladders. due to this fact, I was not fully emptying my bladder when I urinated. when you dont empty your bladder all of the way you get a build up of bacteria which causes utis. anyone can get a distended bladder and be entirely unaware of it. The only thing that can be done for/to prevent a distended bladder is to pee often ( at least once every few hours) all the time every day every week foever. the one time you hold it for a few hours you stretch out your bladder and it becomes distended. of course gradually over time that will shrink back to normal Size but it takes a while and that can leave you vulnerable.
where can I get the gooseberry powder
I really, really need to get help for my dad, who is in his 90’s. He has recurrent UTI’s which are resolved with antibiotics, but eventually the bugs become resistant to the antibiotics. Plus the antibiotics are taking a toll on his body.
I posted here because on the Chris Kresser support page it stated that sometimes Chris’ staff will respond to comments.
I have had no indication that Chris’ staff have actually responded to this forum. As informative as other people’s experiences are, I cannot “experiment” with a very elderly person. Unfortunately, I live in a part of the country where there are no alternative medicine practitioners.
I hope and pray that someone from Chris’ office would respond. Pretty soon, my dad will not have any antibiotics that will work for his condition.
Please help!
Though I am not part of the staff I have been UTI free for nearly 3 yrs while I perform intermittent self catheterization several times daily. Simple things like limiting his sugar and white flour intake (bacteria love both – so, look for or bake/cook alternatives for him), offering him pure cranberry juice like Knudsen brand (I have a glass every night before bed with 2 Solaray D’ Mannose with cranactin capsules), beginning his day with a tsp of d’mannose powder (ClearTract) dissolved in 2 oz of water, additional Solaray d’mannose with cranactin capsules daily and a good refrigerated probiotic daily (read online about them…I use Renew Life brand) Certainly run these items by his physician for approval but, personally, I would prefer to be experimenting with some natural, proven safe approaches such as these than experimenting with the next round of antibiotics. Good luck.
Use to have recurring UTI infections whilst detoxing vigorously, treat them with anti-biotics for the first time then the last time I had it I took 10 tbsps of amla/Indian Gooseberry powder (which is rich in Vitamin C, has 10 times more Vitamin C than oranges), a high dose of Vitamin C between 2000-8000 mg with cranberry juice. Uti gone and hasn’t returned for a year now. Hope that helps anyone out there,
And oh, do not forget to drink lots of water throughout the day.
Please check my answer to Dale
I have been fighting UTI for over a month now. ive been on non stop antibiotics. I have used D-mannose in the past and really seems to work. During this last UTI battle I was diagnosed with a pulmonary embolism and put on Xareltro. Can I take d-mannose and the bio films while on this blood thinner? Of course my pharmacist and family care doc have never heard of d-mannose.
Wow. How can a doctor not have heard of a compound like D-mannose???
There is no meaningful scientific reason to believe that mannose is useful for the prevention or treatment of bladder infections.
http://www.med.nyu.edu/content?ChunkIID=225997
You neglected to include the reason for this conclusion – there is a lack of good studies in humans so all we have to go on is evidence based on animal studies. The lack of evidence is not proof of ineffectiveness. There’s little incentive to research solutions (like d-mannose) that don’t involve patented drugs that bring in big money for the drug companies.
Of course there is no scientific evidence, why would drug companies spend money on research that was going to hurt their profits!!!
We have been getting it online through WellnessPartners.com for a long time. We researched and it was highly recommended. We get UTI Slip D-Mannose, 500 mg. VegeCaps. They ship quickly and have been an excellent company to deal with.
We were told this by American doctors as well even as we sat there telling them that it was a miracle for my daughter. She was having constant infections and they stopped when she started D-Mannose. Each time she felt one coming on, she upped the dose for a few days and voila, gone! We also recommended it to other young women encountering constant infections and it saved their sex lives. We now see an excellent urologist who recommends it to his patients.
Hi. I am glad I go for years without UTI. more than 5yrs, after I found out that plain natural cold yoghurt is the quickest n
cheapest remedy to treat UTI. Sincerely speaking any time I feel like it’s about to start I just rush to the fridge straight to the bathroom and wash my inner parts with yoghurt. Pse try it. stop daouching too. It works 100 percent. Thanks to my late aunt.
How do you insert yoghurt into your bladder – were the e-coli bacterica?
What you are experiencing is a yeast infection, not a bladder or UTI.
I have suffered from E-Coli UTI’s for the past year off and on. They are very painful and after my first bout I learned that Bactrim did nothing but Cipro was a miracle drug. But it is just that a drug, and I do not want to be running to the doc every time symptoms occur. Symptoms came on again 2 days ago, after reading this blog I ran to Whole Foods to pick up some D-Mannos, 100% pure cranberry juice, Keifer for a natural probiotic, Antioxidant and Vitamin C rich fruits. I took 2 D-Mannos pills that day as suggested and mixed a teaspoon of cream of tartar with the juice 3 times throughout the day while also drinking keifer and eating fruits. Within 24 hours I felt a million times better. Now 48 hours later I leaned off the cream of tartar mixture and keifer and still have the feeling of a full bladder and back/kidney pain. I think all of this will eventually cure the UTI but will just take a little longer than a traditional antibiotic would. I am very thankful for all the comments!
Several supplements were mentioned for non-E. coli UTIs, which one would you recommend for a 90yr old woman who has recurring Enterococcus UTIs, alternating with E.coli UTIs? She has been on 6 rounds of various antibiotics and I am afraid they are taking a toll on her body. Thank you.
I will only say that for myself, I noticed the biggest difference when I took cream of tarter (1 tsp in glass of water) a few times a day coupled with the Interfase Enzymes. I can’t be sure which worked better, but it seemed that the cream of tarter worked right away.
I am so glad I found this website and post on treatment alternatives for UTIs. I decided to do one last-ditch internet search for natural alternatives before giving up and calling my doctor to ramp up treatment (which would have involved another expensive, fruitless round of exams by GI experts). I have had recurring UTIs off and on for over 3 years, and in the past few months have been relying on an antibiotic in ever-increasing doses. It had gotten to the point where I was not just taking them after intercourse, but every day- and if I stopped, the pain and cloudy/smelly pee came back. The antibiotics would stop it, but only for as long as I took them (and a yeast infection was never far behind). It was a vicious cycle. I started d-mannose about a month and a half ago, and overlapped w the antibiotics, gradually decreasing the antibiotic dose. I have to say- it WORKS!! I have been antibiotic free – (and UTI- free!) for almost a month! I’ll still be holding my breath for another month or two, but the relief I’ve experienced in the past few weeks has been truly amazing. I feel completely normal again. I only wish I’d found out about this sooner, and I really hope that many, many more women and their doctors will hear about, and consider trying, this safe and effective alternative treatment.
You should get your partner checked out for a UTI as well. If your partner is male, he may be carrying the infection on his skin or near the entrance of his penis, hence reinfecting you. It takes a very advanced stage of UTI before men get painful symptoms. If your partner is infected, even without symptoms, a round of antibiotics can help prevent your partner from being a carrier and hopefully result in fewer infections.